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Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation is allowed to use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website for educational purpose only. Bodily introduction of any kind into humans and animals is strictly forbidden by law. This product should only be handled by licenced qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused as a drug, food and cosmetic.
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For this product you will need: BACTERIOSTATIC WATER For reconstitution.
Tesamorelin is a synthetic 44-amino-acid peptide analogue of growth hormone-releasing hormone, modified with an N-terminal trans-3-hexenoic acid group that confers extended stability in cell culture environments. The structural enhancement supports prolonged in vitro receptor pharmacology investigations relative to native GHRH.
Tesamorelin is a synthetic peptide that is analogous to growth hormone-releasing hormone (GHRH). It binds GHRH receptors in the anterior pituitary and alters GH-related signaling pathways [6]. The peptide consists of 44 amino acids with a trans-3-hexenoic acid modification, which enhances molecular stability and prolongs its half-life relative to endogenous GHRH.
Tesamorelin was originally engineered to explore structural modifications of GHRH for improved receptor binding and pharmacokinetic profiles. Its applications in experimental research include studies of peptide–receptor interactions, intracellular signal transduction, and modulation of the hypothalamic–pituitary–somatotropic axis. Tesamorelin available on our website is supplied exclusively for laboratory, educational, and research purposes.
From Pubchem
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Molecular Formula: C216H360N72O63S Molecular Weight: 5006 g/molSequence: YADAXFXNSYRKVLGQLSARKLLQDXMSRQQGQSNQRGARARL CAS number: 218949-48-5 PubChem CID: 56928011
Tesamorelin is a synthetic GHRH analogue that binds to GHRH receptors in the anterior pituitary and modifies growth hormone–associated signal transduction. It has been employed in experimental studies to analyze of the dynamics of regulation of the somatotropic axis, its receptor–ligand contact, and modulation of downstream intracellular effectors. Structural modifications, such as the trans-3-hexenoic acid group, enhance molecular stability and provide a platform for studying receptor pharmacokinetics and signal transduction under controlled laboratory conditions [1].
Experimental studies with Tesamorelin focus on its role in regulating pathways associated with lipid metabolism and adipose tissue signaling. Acting upon the GHRH receptor, Tesamorelin has the potential to affect and modify the expression and action of specific cellular pathways responsible for lipid mobilization, energy storage, and receptor mediated endocrine communication. The mechanisms underlying such pathways are analyzed at the level of peptide-receptor specificity, signal amplification and feedback regulation in cellular models [2].
Tesamorelin represents a useful instrument to study the communication among neuroendocrine networks as well as regulation of peptide-mediated intracellular signal transduction. Studies investigate it's influences on gamma-aminobutyric acid (GABA) modulation, synaptic signal integration and neuropeptide expression. These studies are restricted to laboratory-based models, focusing on mechanistic signaling pathways rather than functional cognitive outcomes [3].
Tesamorelin is applied in experimental research to study axonal growth, nerve signaling, and intracellular communication within peripheral neural pathways. By modulating GHRH receptor–dependent signaling, it provides a model for studying the kinetics of axonal extension, second-messenger activation, and molecular mechanisms of neuronal signal propagation [4].
Tesamorelin is a research-grade peptide designed for laboratory exploration of growth hormone–related pathways, receptor pharmacology, and intracellular signal transduction. Its stability and receptor specificity make it suitable for studies on somatotropic regulation, lipid signaling networks, neuroendocrine communication, and peripheral signaling mechanisms. Tesamorelin available through Element CRP is supplied exclusively for research and educational purposes and is not intended for clinical or human use. Buy Tesamorelin only if you are a qualified researcher.
Cell-based research with Tesamorelin examines its engagement at the GHRH receptor using transfected cell line backgrounds and primary somatotroph models. Functional characterisation includes Gas/cAMP coupling, PKA activation, and downstream transcriptional responses through CREB-mediated reporter gene assays.
Element CRP supplies this product at 5mg per vial. USA-manufactured via solid-phase peptide synthesis and verified at 99%+ purity by HPLC and Mass Spectrometry. Reconstitution with bacteriostatic water required. Store lyophilised at -20°C; stable for 24 months.
WARNING: For research use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. For use by qualified research professionals only.
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All products on this site are for Research, Development use only. Products are Not for Human consumption of any kind. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.
Element CRP is a chemical supplier. Element CRP is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic act. Element CRP is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic act.
