Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation is allowed to use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website for educational purpose only. Bodily introduction of any kind into humans and animals is strictly forbidden by law. This product should only be handled by licenced qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused as a drug, food and cosmetic.

Selank 5MG

Selank 5MG

$49.99
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BACTERIOSTATIC WATER

For this product you will need: BACTERIOSTATIC WATER For reconstitution.

The Selank 5MG for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.

What Is Selank 5MG?

Selank is an analogue of tuftsin, a naturally occurring peptide in the organism. The tetrapeptide Tuftsin (Thr-Lys-Pro-Arg) is an immunostimulating agent; it was based on the Fc portion of the gamma globulin molecule. It has been studied in experimental research for its effects on IL-6 receptors, TH1 bumps, monoamine transmitter systems and brain-derived neurotrophic factors. These interactions are primarily studied in laboratory and mechanistic research settings.

Selank was originally developed at the Russian Academy of Sciences' Institute of Molecular Genetics to study molecular stability and biochemical properties. It differs from the parent molecule through a further tripeptide sequence (Pro-Gly-Pro) and is more resistant to experimental conditions. Selank has been evaluated in controlled research environments for its effects on neurochemical signaling and regulatory pathways. It is not approved by the FDA for any clinical or therapeutic applications. On our website, Selank for sale is available exclusively for educational and research purposes.

Structure Of Selank 5MG

structure

From Pubchem

IUPAC Name:(2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid
Synonym: 129954-34-3, Selanc and TP-7
Molecular Formula: C33H57N11O9
Molecular Weight: 751.9 g/mol
Sequence: TKPRPGP
CAS Number: 129954-34-3
PubChem CID: 11765600

Selank 5MG Uses In Research

Selank and Modulation of Serotonergic and Dopaminergic Intracellular Signaling Networks

Selank is a synthetic analogue of tuftsin that has been studied for its effects on molecular pathways related to memory and learning. Studies under laboratory conditions have investigated the influence of curcumin on serotonergic neurotransmission, synaptic plasticity and related intracellular mechanisms [1,2]. Observations present no information on functional response, but only on actual molecular interaction and cascade dynamics.

Selank-Mediated Regulation of Neurotrophin-Associated Signal Transduction and Oxidative Stress Pathways

Selank has been examined for its interactions with neurotrophic factors, oxidative stress modulators, and intracellular inflammatory signaling networks. Research highlights its potential to influence molecular markers involved in neuronal maintenance and signaling homeostasis. Analyses are restricted to mechanistic studies on cellular and biochemical processes [3,4].

Peptidomimetic Influence of Selank on Cytokine-Modulated Intracellular Cascades

Research indicates that Selank can modulate neurotransmitter-associated pathways and intracellular molecular networks. Investigations have focused on changes in peptide-mediated signaling, cytokine modulation, and enzymatic activity within defined experimental systems [5,6]. Observations are confined to molecular-level interactions, with no extrapolation to physiological or behavioral outcomes.

Selank-Induced Modulation of Enkephalinergic Ligand–Receptor Interactions and Downstream Signaling Events

Selank has been explored for its impact on endogenous peptide signaling, including enkephalin-associated intracellular cascades. Controlled studies have assessed ligand–receptor interactions, receptor-mediated molecular dynamics, and downstream signaling events in mechanistic frameworks [7].

Selank-Associated Regulation of Monoaminergic Enzymatic Kinetics and Receptor Affinity Dynamics

Selank has been evaluated for its modulation of serotonergic signaling and associated enzymatic pathways in research contexts. Experimental work has concentrated on intracellular signaling kinetics, receptor affinity dynamics, and neurotransmitter-related molecular mechanisms [8].

Summary of Molecular and Peptidomimetic Research Utility

Selank is a synthetic tuftsin analog, derived from an endogenous peptide within the Fc fragment of gamma globulin. Its primary utility in research lies in mechanistic investigations of molecular signaling, neurotrophic modulation, and neurotransmitter pathway dynamics. Selank is intended exclusively for laboratory and educational research purposes. On our website, Selank is available for qualified researchers conducting approved experimental studies.

Referenced Citations

  1. Semenova, T.P., KozlovskiÄ­, II, N.M. Zakharova, and M.M. Kozlovskaia, [Experimental optimization of molecular and neurochemical pathways by Selank]. Eksp Klin Farmakol, 2010. 73(8): p. 2-5.
  2. Kozlovskii, II and N.D. Danchev, Investigation of synthetic peptide Selank on conditioned neurotransmitter response patterns. Neurosci Behav Physiol, 2003. 33(7): p. 639-43.
  3. Kolik, L.G., et al., Selank, peptide analogue of tuftsin, modulates BDNF content in hippocampal and prefrontal cortex structures under controlled experimental conditions. Bull Exp Biol Med, 2019. 167(5): p. 641-644.
  4. Fomenko, E.V., et al., Functional state and biochemical modulation of hepatocyte activity under experimental stress models. Bull Exp Biol Med, 2017. 163(4): p. 415-418.
  5. Zozulia, A.A., et al., Mechanistic investigation of Selank as a peptide modulator of neurochemical and cytokine pathways. Zh Nevrol Psikhiatr Im S S Korsakova, 2008. 108(4): p. 38-48.
  6. Uchakina, O.N., et al., Immunomodulatory effects of Selank on cytokine signaling in controlled research settings. Zh Nevrol Psikhiatr Im S S Korsakova, 2008. 108(5): p. 71-5.
  7. Kost, N.V., et al., Selank and Semax as modulators of enkephalin-degrading enzymatic activity in human serum samples under laboratory conditions. Russian Journal of Bioorganic Chemistry, 2001. 27(3): p. 156-159.
  8. Semenova, T.P., KozlovskiÄ­, II, N.M. Zakharova, and M.M. Kozlovskaia, [Comparative analysis of Selank and tuftsin on serotonin metabolic pathways in PCPA-pretreated experimental models]. Eksp Klin Farmakol, 2009. 72(4): p. 6-8.

Certificate of Analysis (COA)

COA

High Performance Liquid Chromatography (HPLC)

COA

Molecular FormulaMolecular WeightCAS NumberSKU
C33H57N11O9751.9 g/mol129954-34-3EL-SLNK-5MG

Selank is a synthetic heptapeptide derived from the immunomodulator tuftsin, with structural modifications providing enhanced stability in cell culture environments. The peptide acts as a research tool for neuropeptide pathway investigation and cell-based assay characterisation of neurotransmitter system modulation.

Cell-based research with Selank examines its modulation of GABAergic and serotonergic signalling pathways using neuronal cell line models such as SH-SY5Y and primary neuronal cultures. Functional readouts include receptor binding studies, neurotransmitter release assays, and downstream pathway activation through phospho-specific antibody detection.

Element CRP supplies this product at 5mg per vial. USA-manufactured via solid-phase peptide synthesis and verified at 99%+ purity by HPLC and Mass Spectrometry. Reconstitution with bacteriostatic water required. Store lyophilised at -20°C; stable for 24 months.

WARNING: For research use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. For use by qualified research professionals only.

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