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Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation is allowed to use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website for educational purpose only. Bodily introduction of any kind into humans and animals is strictly forbidden by law. This product should only be handled by licenced qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused as a drug, food and cosmetic.
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MK-2866, commonly referred to as ostarine, is a nonsteroidal selective androgen receptor modulator (SARM). It demonstrates selective affinity for androgen receptors expressed in muscle and bone tissue, where it is used in research settings to examine androgen receptor–dependent signaling pathways and gene regulation. Unlike traditional anabolic agents, MK-2866 is characterized by receptor selectivity rather than broad steroidal activity.
The compound was originally created by GTx, Inc. as part of its research program in musculoskeletal and bone-related issues. MK-2866 has been used in lab research studies as a comparison to the other drugs, where it has been shown to be more potent than androgen receptors, with essential selectivity for those organ systems that are anabolic effects on muscle tissue.
MK-2866 is still being studied as a research compound and has not yet had any medical uses granted. MK-2866 for sale offered by Element CRP is strictly intended for research and educational applications only. It is not for animal or human consumption, diagnostic, therapeutic, or any other use. Researchers are obligated to follow the appropriate regulations and guidelines.
From Pubchem
IUPAC Name:(2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamideSynonym: ENOBOSARM, Ostarine, 841205-47-8, GTx-024Molecular Formula: C19H14F3N3O3Molecular Weight: 389.3 g/molCAS Number: 841205-47-8PubChem CID: 11326715
Ostarine (MK-2866) is a representative of a series of non-steroidal selective androgen receptor ligands, like for its receptor-binding characteristics and transcortic activity. At the molecular level, MK-2866 exhibits an affinity for the ligand binding domain of androgen receptor, causing a change in its conformation that alters the recruitment profile of co-factors. This selective binding interaction is unique from steroidal androgenic compounds structurally and functionally.
Receptor-mediated signaling downstream from MK-2866, under in vitro controlled conditions, has been studied in terms of changes in gene expression related to processes such as myofibrillar proteolysis, oxidative metabolism or intracellular signaling pathways. These interactions are investigated mainly for androgen receptor selectivity and tissue-selective transcriptional regulation.
MK-2866 has been explored in non-clinical research settings to assess its interaction with androgen receptor pathways involved in bone matrix regulation. Investigations focus on receptor-mediated transcriptional activity affecting osteogenic signaling networks, extracellular matrix organization, and mineralization-related gene expression.
Experimental observations emphasize the compound’s influence on androgen receptor–responsive elements within bone-associated cellular systems, without engagement of estrogen receptor pathways. These properties make MK-2866 a compound of interest for studying androgen-driven skeletal signaling mechanisms at the molecular level.
Research involving MK-2866 includes evaluation of its role in androgen receptor–linked metabolic signaling. Investigations concentrate on downstream modulation of pathways associated with glucose transport, lipid metabolism, and mitochondrial regulatory processes. Particular emphasis is placed on transcriptional regulators and enzymatic systems influenced by androgen receptor activation.
These analyses are performed for characterization of biochemical interaction profile rather than to define physiological response. These results allow to extend the knowledge on the androgen receptor selectivity and metabolic pathway co-ordination.
MK-2866 has been studied in androgen receptor-positive experimental cellular systems to investigate activity on a receptor-dependent signaling pathway. Studies include ligand-receptor interaction, intracellular signal transduction, and regulation of receptor-mediated transcriptional systems.
These investigations are designed to clarify the role of selective androgen receptor ligands in receptor biology, particularly in systems exhibiting altered androgen receptor expression patterns. No conclusions regarding therapeutic applicability are implied.
MK-2866, also known as Ostarine, is an investigative drug that its use has not yet been approved for any medical condition. It is not approved for human or veterinary use, and has not been authorized for use in food, drugs, or cosmetics.
At Element CRP, MK-2866 for sale is supplied exclusively for research and educational purposes to qualified institutions and professionals. All handling and use must comply with applicable regulatory frameworks governing experimental research compounds. Only buy MK-2866 if you are a licensed researcher.
MK-2866 (Ostarine) is a small-molecule selective androgen receptor modulator (SARM) with a non-steroidal aryl-propionamide structure designed for tissue-selective androgen receptor engagement. Its solution stability supports reproducible behaviour across in vitro nuclear receptor pharmacology research applications.
Cell-based research with MK-2866 examines AR binding affinity and tissue-selective transcriptional regulation in LNCaP, C2C12 myoblast, and osteoblast cell line models. Standard readouts include AR-driven luciferase reporter assays, coactivator recruitment profiling, and target gene expression analysis to characterise tissue-selective pharmacology.
Element CRP supplies this product at 50mg/mL × 30mL. USA-manufactured via chemical synthesis and verified at 99%+ purity by HPLC and Mass Spectrometry. Pre-mixed liquid solution in 30mL or 60mL bottle with dropper; ready for laboratory use. Store at 15-25°C, away from direct light.
WARNING: For research use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. For use by qualified research professionals only.
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All products on this site are for Research, Development use only. Products are Not for Human consumption of any kind. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.
Element CRP is a chemical supplier. Element CRP is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic act. Element CRP is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic act.
