Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation is allowed to use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website for educational purpose only. Bodily introduction of any kind into humans and animals is strictly forbidden by law. This product should only be handled by licenced qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused as a drug, food and cosmetic.

Ipamorelin 5MG

Ipamorelin 5MG

$34.99
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BACTERIOSTATIC WATER

For this product you will need: BACTERIOSTATIC WATER For reconstitution.

The Ipamorelin 5MG for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.

What Is Ipamorelin 5MG?

Ipamorelin is a synthetic pentapeptide in the GHRP family. It is a ghrelin receptor agonist and has been studied for the effects of its antagonism of anterior pituitary somatotrope action in the regulation of pulsatile release growth hormone in laboratory conditions.

Ipamorelin is known as a selective growth hormone secretagogue, focusing on GH out of all the other pituitary hormones such as cortisol, follicle-stimulating hormone, luteinizing hormone and adrenocorticotropic hormone in in-vitro and animal studies. Because of its receptor specificity and signal kinetics, it is a molecule of study for the laboratory. Ipamorelin for sale on our website is intended for research purposes only.

Structure Of Ipamorelin 5MG

structure

From Pubchem

IUPAC Name: (2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
Synonym: Aib-His-2Nal-Phe-Lys-NH2
Molecular Formula: C38H49N9O5
Molecular Weight: 711.9 g/mol
Sequence: XHXFK
CAS Number: 170851-70-4
PubChem CID: 9831659

Ipamorelin 5MG Uses In Research

1. Ipamorelin in Laboratory Research

Ipamorelin is a synthetic pentapeptide that functions as a selective agonist of the ghrelin receptor and a growth hormone secretagogue. Under controlled laboratory conditions, it has been studied for its involvement in growth hormone–associated signaling pathways and its relevance to bone metabolism and tissue turnover research. Experimental investigations have examined ipamorelin’s interaction with receptor-mediated mechanisms and downstream growth factor–related signaling pathways [1].

2. Ipamorelin and Musculoskeletal Pathways

In vitro experimental studies have explored the role of ipamorelin in musculoskeletal cell signaling and tissue remodeling. Research has focused on its interaction with growth hormone secretagogue receptors and downstream pathways such as IGF-1–associated signaling, myoblast proliferation, and differentiation-related molecular markers. Ipamorelin has also been evaluated for its receptor selectivity and limited interaction with other pituitary hormone pathways in controlled research settings [2].

3. Ipamorelin and Glucose-Regulatory Signaling

Laboratory-based investigations have assessed ipamorelin within glucose-related cellular signaling frameworks. Studies have examined its interaction with insulin-associated pathways, receptor-binding dynamics, intracellular calcium signaling, and adrenergic pathway involvement. These evaluations are conducted exclusively within experimental models and do not imply clinical or therapeutic application [3].

4. Summary

Ipamorelin is a synthetic growth hormone secretagogue with specificity for ghrelin receptors. Its receptor-mediated signaling activity continues to be investigated in laboratory research, including pathways related to growth hormone signaling, musculoskeletal systems, and glucose regulation. Research involving IGF-1–associated and bone-related pathways remains ongoing. Ipamorelin supplied by Element CRP is intended strictly for research and educational use and is available only to qualified and licensed investigators.

Referenced Citations

  1. Svensson, J., et al., Analysis of bone mineral–associated parameters following exposure to the growth hormone secretagogues ipamorelin and GH-releasing peptide-6 in controlled experimental systems. Journal of Endocrinology, 2000. 165(3): 569–577.
  2. Johansen, P.B., et al., Evaluation of longitudinal skeletal growth–related markers following application of the growth hormone-releasing peptide ipamorelin in a structured research environment. Growth Hormone & IGF Research, 1999. 9(2): 106–113.
  3. Andersen, N.B., et al., Investigation of bone formation–related signaling markers under glucocorticoid exposure with concurrent assessment of the growth hormone secretagogue ipamorelin in experimental settings. Growth Hormone & IGF Research, 2001. 11(5): 266–272.
  4. Greenwood-Van Meerveld, B., et al., Examination of gastrointestinal motility–associated parameters following administration of the ghrelin mimetic ipamorelin within a postoperative dysmotility research model. Journal of Experimental Pharmacology, 2012. 4: 149–155.
  5. Beck, D.E., et al., Randomized, controlled exploratory investigation assessing pharmacodynamic endpoints associated with the ghrelin mimetic ipamorelin in a postoperative gastrointestinal research context. International Journal of Colorectal Disease, 2014. 29(12): 1527–1534.
  6. Adeghate, E. and A.S. Ponery, Mechanistic evaluation of ipamorelin-associated insulin signaling pathways observed in isolated pancreatic tissue under controlled experimental conditions. Neuro Endocrinology Letters, 2004. 25(6): 403–406.

Certificate of Analysis (COA)

COA

High Performance Liquid Chromatography (HPLC)

COA

Mass Spectrometry (MS)

COA

Molecular FormulaMolecular WeightCAS NumberSKU
C38H49N9O5711.9 g/mol170851-70-4ES-IPA-5

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue with a structure optimised for selective engagement of the ghrelin receptor (GHSR-1a) without cross-reactivity at unrelated GPCRs. Its compact peptide architecture provides reliable stability across in vitro buffer systems and supports reproducible cell-based receptor pharmacology characterisation.

Cell-based assay research with Ipamorelin examines selective GHSR-1a agonist activity using receptor-transfected HEK293 and CHO-K1 cell lines, with Gaq/PLC coupling and intracellular calcium mobilisation as primary functional readouts. Comparative selectivity profiling against related growth hormone secretagogues maps its distinct pharmacological signature in receptor pharmacology research.

Element CRP supplies this product at 5mg per vial. USA-manufactured via solid-phase peptide synthesis and verified at 99%+ purity by HPLC and Mass Spectrometry. Reconstitution with bacteriostatic water required. Store lyophilised at -20°C; stable for 24 months.

WARNING: For research use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. For use by qualified research professionals only.

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