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Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation is allowed to use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website for educational purpose only. Bodily introduction of any kind into humans and animals is strictly forbidden by law. This product should only be handled by licenced qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused as a drug, food and cosmetic.
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For this product you will need: BACTERIOSTATIC WATER For reconstitution.
Growth hormone–releasing peptide-2 (GHRP-2), also known as pralmorelin, is a type of synthetic hexapeptide, has had biochemical and molecular studies venturing that metabolic systems activate somatostatin against it. Structurally, GHRP-2 is a member of short chain peptides which have been studied for their receptor binding characteristics and signal transduction properties under controlled experimental conditions. Its molecular conformation and stability profile have made it a subject of interest in studies focused on peptide–receptor affinity and endocrine signaling architecture.
Within experimental research settings, GHRP-2 has been utilized as a model compound for examining growth hormone–associated signaling pathways and regulatory network interactions at the cellular and molecular level. Scientific investigations have primarily emphasized its physicochemical properties, receptor selectivity, and mechanistic relevance in in vitro analytical frameworks. GHRP-2 is not approved by the FDA for therapeutic or diagnostic use. GHRP-2 offered by Element CRP is intended strictly for research and educational purposes only and is supplied exclusively to qualified laboratories.
From Pubchem
IUPAC Name:(2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-aminopropanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamideSynonym: Pralmorelin, 158861-67-7 and KP-102Molecular Formula: C45H55N9O6Molecular Weight: 818.0 g/molSequence: AXAWFKCAS Number: 158861-67-7PubChem CID: 6918245
GHRP-2 has been incorporated into experimental research paradigms examining ghrelin-receptor–linked signaling architectures implicated in inflammatory pathway regulation. Investigative focus has centered on the interaction between growth hormone secretagogue receptor (GHS-R) activation and downstream cytokine-associated signaling networks, including transcriptional and post-transcriptional modulators involved in inflammatory mediator expression.
Additional exploratory studies have utilized GHRP-2 as a molecular probe to assess its influence on nitric oxide–associated pathways, immune cell signaling intermediates, and intracellular regulatory mechanisms governing inflammatory signal transduction under controlled experimental conditions [1,2].
GHRP-2 has been examined within research settings investigating neuroendocrine signaling systems involved in appetite and energy homeostasis. As a ghrelin receptor agonist, GHRP-2 has been employed to study ligand-receptor dynamics, hypothalamic signaling integration, and neuropeptide communication networks associated with feeding-related regulatory processes.
These investigations emphasize molecular and biochemical signaling interactions rather than phenotypic or functional outcomes, positioning GHRP-2 as a research compound of interest for elucidating appetite-associated signaling circuitry [3,4].
Experimental literature has explored GHRP-2 within cardiovascular research frameworks to examine its association with receptor-mediated signaling pathways relevant to myocardial cellular organization and stress-response modulation. Research attention has focused on molecular pathways implicated in oxidative signaling balance, intracellular remodeling processes, and cardiac tissue signaling dynamics under laboratory conditions.
Such studies contribute to broader efforts aimed at characterizing ghrelin-related peptide interactions within cardiovascular molecular research models [5,6].
GHRP-2 has been incorporated into experimental investigations addressing neuroendocrine mechanisms linked to sleep-associated signaling regulation. Research has examined its interaction with pathways related to circadian rhythm modulation, growth hormone–associated signaling cascades, and sleep architecture–related neurochemical processes.
Findings across studies remain heterogeneous, and continued research efforts seek to further clarify the relevance of ghrelin receptor activation within sleep-associated signaling systems [7,8].
Laboratory-based research has evaluated GHRP-2 as an experimental compound for studying skeletal muscle–associated signaling pathways. Investigations have examined molecular markers related to protein turnover regulation, growth hormone–linked transcriptional activity, and intracellular pathways involved in tissue remodeling and inflammatory signaling integration.
Within these contexts, GHRP-2 is utilized as a biochemical research tool to explore muscle-related signaling networks rather than to assess functional performance or therapeutic outcomes [9,10].
GHRP-2 is a synthetic hexapeptide investigated within experimental and preclinical research environments for its interaction with ghrelin-associated receptor systems and downstream signaling pathways. Scientific literature has explored its relevance across inflammation-associated signaling, appetite-related neuroendocrine mechanisms, cardiovascular molecular frameworks, sleep-associated regulation, and skeletal muscle signaling research.
GHRP-2 is not approved by the FDA for therapeutic or diagnostic use. GHRP-2 supplied by Element CRP is provided exclusively for research and educational purposes and is intended for use by licensed institutions and qualified research professionals only.
GHRP-2 is a synthetic hexapeptide growth hormone secretagogue with a structurally optimised sequence for engagement at the ghrelin receptor (GHSR-1a). Its compact peptide architecture supports stable performance across standard in vitro assay buffer systems and cell culture environments.
Cell-based research with GHRP-2 focuses on GHSR-1a receptor pharmacology using transfected HEK293 and CHO-K1 cell lines, with intracellular calcium mobilisation through Gaq/PLC coupling as the primary functional readout. Comparative selectivity studies map its distinct profile against alternative growth hormone-releasing peptides in receptor pharmacology research.
Element CRP supplies this product at 5mg per vial. USA-manufactured via solid-phase peptide synthesis and verified at 99%+ purity by HPLC and Mass Spectrometry. Reconstitution with bacteriostatic water required. Store lyophilised at -20°C; stable for 24 months.
WARNING: For research use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. For use by qualified research professionals only.
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Element CRP is a chemical supplier. Element CRP is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic act. Element CRP is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic act.
